MUVON Therapeutics AG

Regain control through personalized muscle regeneration

Our aim is to establish personalized treatments to help patients with Stress Urinary Incontinence regain control of their lives by offering them minimally invasive, low-risk treatments for the regeneration of skeletal muscle tissue.
MUVON Key Visual

Project Overview

Affiliation

Year of Acceptance

Status

Team size

Project Description

Stress urinary incontinence is a highly prevalent and underdiagnosed disorder that affects over 200 million people worldwide. Women are affected twice as often as men, with an estimated 40% of women above the age of 40 suffering from SUI. It has a severe impact on physical and psychological health, and existing treatment options offer only short-lived relief or involve synthetic implants with inherent complications.

During their time at Wyss Zurich, the MUVON team developed a low-risk, minimally invasive treatment against SUI and confirmed safety and feasibility of the tissue therapy in clinical trials. In this treatment, the patient’s own muscle precursor cells (MPC) are isolated, expanded in the lab, and re-injected into the patient’s sphincter muscle. These cells regenerate the damaged tissue and restore function.

Project Contact

Deana Mohr

Project Leader

Daniel Eberli

Faculty Mentor

Project Partners

University Hospital Zurich, University of Zurich, BioEntrpreneurship & Innovation (BEI) Program, University of Zurich, Translational Medicine Accelerator

Funding Partners

UZH Entrepreneur Fellowship, EU Horizon 2020, Innosuisse, Lichtsteiner Foundation, Venturelab, Werner Siemens Foundation

Project Updates

Another amazing presence for Wyss Zurich startups at the 15th TOP 100 Swiss Startup Award!
The International Data Safety Monitoring Board has recommended the continuation of MUVON Therapeutic AG’s SUISSE MPC2 study, an indication that the startup is on schedule for the release of the final data and completion of the phase II study scheduled for Q3 2025.
With its therapy rooted in tissue engineering, MUVON Therapeutics AG is developing a low-risk, minimally invasive treatment that uses the patient’s own muscle precursor cells (MPC) to regenerate the damaged sphincter muscle to treat stress urinary incontinence (SUI).
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